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Archivio digitale delle tesi discusse presso l’Università di Pisa

Tesi etd-11122012-235741


Tipo di tesi
Tesi di laurea specialistica
Autore
ANGELINI, LORENZA
URN
etd-11122012-235741
Titolo
Investigation of possible strategies for intraoperative bowel cleaning
Dipartimento
INGEGNERIA
Corso di studi
INGEGNERIA BIOMEDICA
Relatori
tutor Prof. Valdastri, Pietro
relatore Prof.ssa Menciassi, Arianna
Parole chiave
  • colonoscopia
  • getti d'acqua ad alta pressione
  • preparazione dell'intestino
  • ultrasuoni
Data inizio appello
04/12/2012
Consultabilità
Non consultabile
Data di rilascio
04/12/2052
Riassunto
One of the main challenges with the conventional colonoscopy is bowel cleansing before the examination. Despite the variety of methods available, incomplete bowel preparation is reported in up to 20% of patients, resulting in aborted procedures in 6%. In fact the current cleansing agents on the market, including generally polyethylene glycol solutions, oral sodium phosphate and stimulants often result inconvenient, unpleasant and intolerable for the patient, causing abdominal cramping, nausea, vomiting, electrolyte imbalance and renal failure. Moreover an imperfect preparation impacts negatively on the diagnostic accuracy, compromising the visualization of the colonic mucosa and the detection of polyps and lesions. Consequently it can lead to prolonged procedure time and the repetition of the exam at earlier intervals, raising costs by 12% to 22% due to aborted examination. It would, therefore, be necessary to provide a novel method that overcomes the undesirable effects of the traditional cleansing.
The aim of this thesis was to investigate alternative strategies to cleanse the large intestine prior to colonoscopy.
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