Tesi etd-11112019-184821 |
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Tipo di tesi
Tesi di laurea magistrale
Autore
DE RUGGIERO, MARCO
URN
etd-11112019-184821
Titolo
Novel Approaches to Engineer the Human Heart Microenvironment Using 3D Bioprinting Technologies
Dipartimento
INGEGNERIA DELL'INFORMAZIONE
Corso di studi
INGEGNERIA BIOMEDICA
Relatori
relatore Prof. Vozzi, Giovanni
relatore Prof. Gentile, Carmine
relatore Prof. Gentile, Carmine
Parole chiave
- Cells Culture
- In vitro models
- Purfusable Chamber
- Tissue Engineer
Data inizio appello
06/12/2019
Consultabilità
Non consultabile
Data di rilascio
06/12/2089
Riassunto
The heart microenvironment is critical for the optimal supply of blood to any tissue in our body, mimicking the complexity of the human heart is been a challange for many years.
The focus of thesis is the engineering of a novel device to better recapitulate the cardiac microenvironment in an in vitro model. In order to achieve this, a thorough understanding of the main components of human heart microenvironment is required and will be the focus of this thesis as well. Then, a combination of cell culture, fluidodynamics and bioprinting technologies will be implemented to fabricate the in vitro model.
The focus of thesis is the engineering of a novel device to better recapitulate the cardiac microenvironment in an in vitro model. In order to achieve this, a thorough understanding of the main components of human heart microenvironment is required and will be the focus of this thesis as well. Then, a combination of cell culture, fluidodynamics and bioprinting technologies will be implemented to fabricate the in vitro model.
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