• Myocardial regeneration
• PLGA
• Tissue engineering

The goal of the project is the preparation and development of integrated patches with adequate characteristics to be used in myocardium tissue regeneration on the basis of morphological, mechanical and degradation characterization, mimicking anisotropic structure and mechanical properties of the myocardium. A crucial objective of this work was also to develop a scaffold addressing an important strategy of therapies in human cardiology.Towards this goal, we thought to produce biodegradable nanoparticles able to release in a controlled manner a recruitment factor of stem cell to allow vascularization and cardioprotection.