Tesi etd-11072024-094606 |
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Tipo di tesi
Tesi di specializzazione (4 anni)
Autore
MATTII, MARTINA
URN
etd-11072024-094606
Titolo
Impact of preoperative MRI on surgical management in early-stage breast cancer: a Pisa experience.
Dipartimento
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Corso di studi
RADIODIAGNOSTICA
Relatori
relatore Prof. Neri, Emanuele
correlatore Dott.ssa Cossu, Maria Cristina
correlatore Dott.ssa Cossu, Maria Cristina
Parole chiave
- BCS
- breast cancer
- chirurgia
- mammella
- mastectomia
- mastectomy
- MRI
- preoperative
- preoperatoria
- RM
- stadi precoci
- surgery
- tumore
Data inizio appello
09/12/2024
Consultabilità
Non consultabile
Data di rilascio
09/12/2094
Riassunto
Aim: The roles of MX and US in the preoperative evaluation of breast cancer are quite defined; instead, the role of MRI in this setting is still under examination. We have conducted a retrospective observational study with the purpose of understand if there is, in our experience, an increased number of ipsilateral and contralateral mastectomy in patients underwent to MRI.
Materials and method: We collect all the patients underwent to surgery for early-breast cancer in 2023 and we divided the included patients in two groups: MRI group with the patients who underwent 3T MRI before treatment and CONTROL group with patients who received surgical management without preoperative MRI.
Results: In the MRI group there are 46 BCS and 29 mastectomies, of which 5 bilateral mastectomies and 1 bilateral BCS; in MRI group there were no reinterventions. In CONTROL group are included 294 patients; of them, we had 213 BCS and 100 mastectomies with 19 bilateral surgeries with 7 patients underwent to bilateral mastectomies, 9 to bilateral BCS and 3 to BCS in one breast and to mastectomy to the other; in CONTROL group there were 2 reinterventions. Our statistical analysis haven’t revealed a statistically significant difference of the number of mastectomies between two group; at a multivariate analysis we have found out that people with mutation like BCRA have more frequently mastectomy (p = 0,056), and people older have more frequent BCS (p<0.001).
Conclusion: According to some article in literature pre-operative MRI doesn’t have an impact on the number of mastectomies if compared to a non -MRI group. We suppose that if multicentric regional study will be performed this result could change because of the selection of patients and the surgical preference of our centre.
Materials and method: We collect all the patients underwent to surgery for early-breast cancer in 2023 and we divided the included patients in two groups: MRI group with the patients who underwent 3T MRI before treatment and CONTROL group with patients who received surgical management without preoperative MRI.
Results: In the MRI group there are 46 BCS and 29 mastectomies, of which 5 bilateral mastectomies and 1 bilateral BCS; in MRI group there were no reinterventions. In CONTROL group are included 294 patients; of them, we had 213 BCS and 100 mastectomies with 19 bilateral surgeries with 7 patients underwent to bilateral mastectomies, 9 to bilateral BCS and 3 to BCS in one breast and to mastectomy to the other; in CONTROL group there were 2 reinterventions. Our statistical analysis haven’t revealed a statistically significant difference of the number of mastectomies between two group; at a multivariate analysis we have found out that people with mutation like BCRA have more frequently mastectomy (p = 0,056), and people older have more frequent BCS (p<0.001).
Conclusion: According to some article in literature pre-operative MRI doesn’t have an impact on the number of mastectomies if compared to a non -MRI group. We suppose that if multicentric regional study will be performed this result could change because of the selection of patients and the surgical preference of our centre.
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