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Tesi etd-11072024-094606


Tipo di tesi
Tesi di specializzazione (4 anni)
Autore
MATTII, MARTINA
URN
etd-11072024-094606
Titolo
Impact of preoperative MRI on surgical management in early-stage breast cancer: a Pisa experience.
Dipartimento
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Corso di studi
RADIODIAGNOSTICA
Relatori
relatore Prof. Neri, Emanuele
correlatore Dott.ssa Cossu, Maria Cristina
Parole chiave
  • BCS
  • breast cancer
  • chirurgia
  • mammella
  • mastectomia
  • mastectomy
  • MRI
  • preoperative
  • preoperatoria
  • RM
  • stadi precoci
  • surgery
  • tumore
Data inizio appello
09/12/2024
Consultabilità
Non consultabile
Data di rilascio
09/12/2094
Riassunto
Aim: The roles of MX and US in the preoperative evaluation of breast cancer are quite defined; instead, the role of MRI in this setting is still under examination. We have conducted a retrospective observational study with the purpose of understand if there is, in our experience, an increased number of ipsilateral and contralateral mastectomy in patients underwent to MRI.
Materials and method: We collect all the patients underwent to surgery for early-breast cancer in 2023 and we divided the included patients in two groups: MRI group with the patients who underwent 3T MRI before treatment and CONTROL group with patients who received surgical management without preoperative MRI.
Results: In the MRI group there are 46 BCS and 29 mastectomies, of which 5 bilateral mastectomies and 1 bilateral BCS; in MRI group there were no reinterventions. In CONTROL group are included 294 patients; of them, we had 213 BCS and 100 mastectomies with 19 bilateral surgeries with 7 patients underwent to bilateral mastectomies, 9 to bilateral BCS and 3 to BCS in one breast and to mastectomy to the other; in CONTROL group there were 2 reinterventions. Our statistical analysis haven’t revealed a statistically significant difference of the number of mastectomies between two group; at a multivariate analysis we have found out that people with mutation like BCRA have more frequently mastectomy (p = 0,056), and people older have more frequent BCS (p<0.001).
Conclusion: According to some article in literature pre-operative MRI doesn’t have an impact on the number of mastectomies if compared to a non -MRI group. We suppose that if multicentric regional study will be performed this result could change because of the selection of patients and the surgical preference of our centre.
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