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Archivio digitale delle tesi discusse presso l’Università di Pisa

Tesi etd-11052022-181250


Tipo di tesi
Tesi di laurea magistrale
Autore
ROSSI, ANNACHIARA
URN
etd-11052022-181250
Titolo
Glycoconjugated metal complexes as anticancer and diagnostic agents
Dipartimento
CHIMICA E CHIMICA INDUSTRIALE
Corso di studi
CHIMICA
Relatori
relatore Prof.ssa Di Bussolo, Valeria
relatore Prof. Marchetti, Fabio
controrelatore Prof.ssa Gabbiani, Chiara
Parole chiave
  • anticancer
  • diiron complexes
  • europium
  • glycoconjugated
  • lanthanide-based
  • probes
Data inizio appello
12/12/2022
Consultabilità
Tesi non consultabile
Riassunto
The work carried out in this thesis has focused on the synthesis of glycoconjugated lanthanide-based complexes as molecular probes and aminocarbyne diiron complexes with terminal glycoconjugated and non-glycoconjugated pyridine ligands. The molecules have been designed for applications in cancer diagnosis and therapy, respectively. The intention has been to exploit the high glycolytic metabolism characteristic of cancer cells, so as to allow greater internalisation of the molecules via the membrane transporters GLUTs.
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