ETD

Archivio digitale delle tesi discusse presso l’Università di Pisa

Tesi etd-11052022-181250

Tipo di tesi

Tesi di laurea magistrale

URN

etd-11052022-181250

Titolo

Glycoconjugated metal complexes as anticancer and diagnostic agents

Dipartimento

CHIMICA E CHIMICA INDUSTRIALE

Corso di studi

CHIMICA

Parole chiave

anticancer
diiron complexes
europium
glycoconjugated
lanthanide-based
probes

Data inizio appello

12/12/2022

Consultabilità

Tesi non consultabile

Riassunto (Inglese)

Riassunto (Italiano)

The work carried out in this thesis has focused on the synthesis of glycoconjugated lanthanide-based complexes as molecular probes and aminocarbyne diiron complexes with terminal glycoconjugated and non-glycoconjugated pyridine ligands. The molecules have been designed for applications in cancer diagnosis and therapy, respectively. The intention has been to exploit the high glycolytic metabolism characteristic of cancer cells, so as to allow greater internalisation of the molecules via the membrane transporters GLUTs.

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Tesi non consultabile. Contatta l’autore