• contraccettivi orali
• fattori di rischio
• stati trombofilici
• stroke
• trombosi venose cerebrali

Cerebral sinus venous thrombosis (CSVT) is a rare condition representing the 0.5-1% of all stroke
cases which can have serious consequences. Early diagnosis and complete screening for acquired or
inherited risk factors is crucial for decreasing morbidity and mortality. We have investigated clinical and etiological factors in an Italian cohort of 43 patients with CSVT. Common presentation complaints were headache (81.4%), focal signs (20.9%), vomiting (11.6%), and seizures (6.9%). Acquired or inherited conditions were observed in more than 80% of cases. The commonest etiological factors were contraceptives (74.1% of females), congenital thrombophilia (34.9%), infections and dysthyroidism (16.3%), iperhomocysteinemia (9.3%), migraine (11.6%), cranial trauma (9.3%), and chronic myeloproliferative diseases (11.6%). Outcome was favourable in more than 80% of patients. Early diagnosis and anticoagulant treatment may decrease mortality and/or morbidity rates related with CVST in these patients. Thrombophilic abnormalities, either inherited or acquired, are worthy to be widely investigated.