• pharyngectomy
• infrahyoid flap
• pedicled flap
• laryngectomy
• partial
• hypopharyngeal carcinoma

Aims. We evaluated a cohort of advanced hypopharyngeal squamous cell carcinoma, treated with conservative surgery, reconstruction with infrahyoid flap and radio-chemotherapy.
Methods. We used partial laryngopharyngectomy and radio-chemotherapy to treat fifty-seven patients with stage III-IV hypopharyngeal SCC from November 1994 to December 2011. Clinical examination and speech therapy evaluation were used for estimation of laryngeal function.
Results. All patients received a partial laryngopharyngectomy. All patients underwent neck dissection; 56 patients received bilateral neck dissection. Reconstruction was achieved by infra-hyoid flap. Five-year overall and disease-specific survival rates were 54,4% and 61,4%, respectively. Successful laryngeal function preservation with complete five-years remission was achieved in 44% of the patients.
Conclusion. Selected even if advanced carcinomas of the hypopharynx maybe treated with partial laryngopharyngectomy with reconstruction with pedicled flap. Both oncological and functional results showed a good outcome.