Tesi etd-06162021-150927 |
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Tipo di tesi
Tesi di laurea magistrale
Autore
PARRA, GIULIA
URN
etd-06162021-150927
Titolo
Ottimizzazione e caratterizzazione di un prototipo di patch cardiaco per la rigenerazione del miocardio infartuato
Dipartimento
INGEGNERIA DELL'INFORMAZIONE
Corso di studi
INGEGNERIA BIOMEDICA
Relatori
relatore Prof.ssa Cascone, Maria Grazia
relatore Dott.ssa Cristallini, Caterina
controrelatore Prof.ssa Ahluwalia, Arti Devi
relatore Dott.ssa Cristallini, Caterina
controrelatore Prof.ssa Ahluwalia, Arti Devi
Parole chiave
- tissue engineering
- cardiac patch
- acute myocardial infarction
Data inizio appello
16/07/2021
Consultabilità
Non consultabile
Data di rilascio
16/07/2091
Riassunto
The purpose of this thesis work consists in the optimization of the preparation procedure of an implantable, biodegradable, micro-structured cardiac patch in view of a possibile technological transfer.
The physicochemical, mechanical and functional characterization of the product was performed at different phases of the production process.
The patch was also functionalised with adenosine in order to obtain a patch able to regenerate the myocardial tissue and simultaneously protect from reperfusion injury after myocardial infarction.
The physicochemical, mechanical and functional characterization of the product was performed at different phases of the production process.
The patch was also functionalised with adenosine in order to obtain a patch able to regenerate the myocardial tissue and simultaneously protect from reperfusion injury after myocardial infarction.
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