ETD

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Tesi etd-05122013-155725

Tipo di tesi

Tesi di laurea magistrale

URN

etd-05122013-155725

Titolo

Analysis of genomic and metagenomic libraries of marine epiphytic bacteria to isolate and characterize the antinematode activity when screened against Caenorhabditis elegans.

Dipartimento

BIOLOGIA

Corso di studi

BIOLOGIA MARINA

Parole chiave

antinematode
Caenorhabditis elegans
fosmid libraries
functional genomic screen
functional metagenomic screen
marine bacteria
marine bioactives

Data inizio appello

13/06/2013

Consultabilità

Non consultabile

Data di rilascio

13/06/2053

Riassunto (Inglese)

Riassunto (Italiano)

The main purpose of this thesis was to screen genomic and metagenomic libraries of epiphytic bacterial communities previously isolated from the surface of marine seaweed Ulva australis and Delisea pulchra. Through functional screening against the nematode Caenorhabditis elegans, the bacterial clones at the subject of this thesis have been characterized for their antinematodal activity. Here I showed that marine microorganisms are a source of bioactivity against the nematode C. elegans and those bacterial secondary metabolites might lead in the long terms to pharmaceuticals and better nematode management strategies.

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