ETD

Archivio digitale delle tesi discusse presso l'Università di Pisa

Tesi etd-03132012-144513


Tipo di tesi
Tesi di dottorato di ricerca
Autore
DONATINI, GIANLUCA
URN
etd-03132012-144513
Titolo
Potential Biomarkers of thyroid neoplasia: the impact of proteomics analysis in the diagnosis.
Settore scientifico disciplinare
MED/18
Corso di studi
SCIENZE CHIRURGICHE, ANESTESIOLOGICHE E DELL'EMERGENZA
Relatori
tutor Prof. Iacconi, Pietro
Parole chiave
  • proteomics analysis
  • biomarkers.
  • Thyroid neoplasia
Data inizio appello
23/03/2012
Consultabilità
Completa
Riassunto
Fine-needle aspiration cytology (FNA) is the most important tool to correctly address a thyroid lesion. Thyroid cancers account for about 5% of all lesions. A correct diagnosis may be difficult using FNA. Thyroid biomarkers help to better characterized thyroid lesions. Among the new techniques, proteomics , since 2002, has been increasingly used. In this thesis we describe the results obtained by the proteomic analysis of thyroid FNA to detect potential biomarkers for thyroid neoplasia and its impact in clinical management of thyroid malignancies.

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