Tesi etd-03122022-194851 |
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Tipo di tesi
Tesi di laurea magistrale
Autore
CHESI, MATTIA
URN
etd-03122022-194851
Titolo
Development of a ligandless palladium-catalyzed direct arylation on 1-methylindazole
Dipartimento
CHIMICA E CHIMICA INDUSTRIALE
Corso di studi
CHIMICA
Relatori
relatore Prof. Bellina, Fabio
Parole chiave
- arylation
- direct
- indazole
Data inizio appello
30/03/2022
Consultabilità
Non consultabile
Data di rilascio
30/03/2025
Riassunto
Development of a novel reaction to introduce an aryl fragment on C-3 position of 1H-indazole cores without the employment of ligands. In an industrial context, a direct arylation that doesn't require ligands or additive to add in the reaction procedure, makes the process sustainable and with a less environmental impact. We decided to study this heteroaromatic core for its great and potential pharmacological properties.
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