Tesi etd-03012024-114240 |
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Tipo di tesi
Tesi di laurea magistrale
Autore
STURLESE VERDURI, ARIANNA
URN
etd-03012024-114240
Titolo
Interacting with peritumoral parvalbumin interneurons to counteract Glioblastoma growth
Dipartimento
BIOLOGIA
Corso di studi
NEUROSCIENCE
Relatori
relatore Vannini, Eleonora
Parole chiave
- GABA
- Glioblastoma
- inhibitory system
- mouse model
Data inizio appello
08/04/2024
Consultabilità
Non consultabile
Data di rilascio
08/04/2064
Riassunto
This project aimed at dissecting the role of parvalbumin interneurons during GB growth. To address this issue, I used techniques such as chemogenetics, motor tests, MRI and immunohistochemistry analyses.
Given the complex relationship between GB and the peritumoral tissue, it is of paramount importance to understand and dissect the role of all the players in order to add useful information to develop more effective therapeutic approaches aimed at ameliorating patients’ quality of life and survival.
Given the complex relationship between GB and the peritumoral tissue, it is of paramount importance to understand and dissect the role of all the players in order to add useful information to develop more effective therapeutic approaches aimed at ameliorating patients’ quality of life and survival.
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