ETD

Archivio digitale delle tesi discusse presso l'Università di Pisa

Tesi etd-02062020-114354


Tipo di tesi
Tesi di laurea magistrale
Autore
GRAVINA, ALESSIO
URN
etd-02062020-114354
Titolo
Machine learning prediction of compounds impact on Schizophrenia treatment
Dipartimento
INFORMATICA
Corso di studi
INFORMATICA
Relatori
relatore Bacciu, Davide
relatore Priami, Corrado
relatore Grimes, Kevin
Parole chiave
  • Molecular fingerprint
  • Machine Learning
  • Graph learning
  • Schizophrenia
Data inizio appello
06/03/2020
Consultabilità
Completa
Riassunto
The thesis discusses the use of Machine Learning models to predict compounds that can reduce glial phagocytic activity in Schizophrenia patients. The used approach is based on the generation of a molecular fingerprint through a graph Machine Learning technique called graph convolution. The analysis has been performed in collaboration with the SPARK research group at Stanford, that has provided the data.
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