Tipo di tesi
Tesi di laurea magistrale
Titolo
Amino-derivatives of isohexides as chiral building blocks for the synthesis of CSA for NMR spectroscopy
Dipartimento
CHIMICA E CHIMICA INDUSTRIALE
Riassunto (Italiano)
Synthesis and characterization of diamine and aminoalcohol derivatives from isohexides, through stereospecific and regioselective reactions. These new chiral building blocks have been used for the development of regioselective and stereospecific protocols for the preparation of new arylureas, arylthioureas and arylamides with different stereochemistry and functionalization. These new chiral auxiliaries have been employed as chiral solvating agents for NMR spectroscopic enantiodiscrimination of derivatized aminoacids, to study the influence of different parameters such as stereochemistry and/or derivatization of the scaffold on their chiral recognition capability.
