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Digital archive of theses discussed at the University of Pisa

 

Thesis etd-12232021-162022


Thesis type
Tesi di specializzazione (4 anni)
Author
MALFATTI, GIULIA
URN
etd-12232021-162022
Thesis title
Functional assessment of dysphagia in head and neck tumors and correlation with perceived quality of life
Department
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Course of study
RADIOTERAPIA
Supervisors
relatore Dott. Ursino, Stefano
Keywords
  • dysphagia
  • RID
  • FEES
  • videofluoroscopy
  • MDADI
  • radioterapy
  • head and neck cancer
  • swallow
  • life quality
Graduation session start date
11/01/2022
Availability
Withheld
Release date
11/01/2092
Summary
In head and neck cancer (HNC) patients, radiation induced dysphagia (RID) is a very common side effect and has a significant impact on patient’s quality of life (QoF). The aim of this study is to evaluate the functional assessment of RID and correlation with perceived QoF. We evaluate a coort of 56 HNC patients treated with chemoradiotherapy on nasopharynx and oropharynx districts, between August 2015 and October 2021. All patients underwent to MD Anderson Dysphagia Inventory (MDADI) test for the evaluation of swallowing related QoL, FEES and videofluoroscopy (VFS) at t0 (time 0), t6 (after 6 months) and t12 (after 12 month). MDADI test is a written, 20 item self-amministred questionnaire; we mainly use a summary score called composite (MDADI-C) at time 0, and then after 6 and 12 months after chemo-radiotherapy. We correlate the MDADI – C score at t0, t6 and t12 to the results of FEES and VFS at the same time and their variation during the study to establish a link between patient’s self-perception of dysphagia links and FEES or VFS. We find that FEES is probably linked with MDADI-C variation (even though this results is not statistically significative) whereas VFS does not.
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