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Tesi etd-10152020-225004


Tipo di tesi
Tesi di specializzazione (4 anni)
Autore
CASINI, CHIARA
URN
etd-10152020-225004
Titolo
Reduced field-of-view versus large field-of-view diffusion-weighted MRI in the evaluation of pancreatic lesions.
Dipartimento
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Corso di studi
RADIODIAGNOSTICA
Relatori
relatore Prof. Caramella, Davide
relatore Dott. Boraschi, Piero
Parole chiave
  • diffusion-weighted imaging
  • magnetic resonace imaging
  • pancreas
  • reduced field of view
  • solid lesions
Data inizio appello
07/11/2020
Consultabilità
Completa
Riassunto
Purpose: To compare image quality, presence of artifacts and apparent diffusion coefficient (ADC) values between reduced field-of-view (FOV) and large FOV single-shot (SS) echo-planar imaging (EPI) diffusion-weighted imaging (DWI).
Materials and methods: From our radiological database we retrospectively selected 3T MR examinations (GE Discovery MR750; GE Healthcare) of 60 patients with solid pancreatic lesions. Two readers independently performed qualitative analysis and calculated by consensus quantitative ADC values of solid pancreatic lesions in both large FOV and reduced FOV DWI. The qualitative analysis parameters included: 1) Sharpness, 2) Distortion, Ghosting, Motion and Susceptibility artifacts, 3) Lesion Conspicuity and 4) Overall Image Quality. These parameters were evaluated using a 4-point scale. T-test for paired data was used to compare qualitative scores and ADC values between large FOV and reduced FOV DWI, as well as to assess inter-reader agreement.
Results: On qualitative analysis, the scores of reduced FOV DWI were better for sharpness (2.68 ± 0.71), artifacts (2.62 ± 0.71) and overall image quality (2.82 ±0.73) as compared to large FOV DWI (sharpness, 2.45 ± 0.55; artifacts, 2.42 ± 0.58; overall image quality, 2.59 ± 0.56) (p < 0.05). No significant difference was found for lesion conspicuity (2.89 ± 0.85 at reduced FOV and 2.78 ± 0.90 at large FOV DWI) (p > 0.05). On quantitative analysis, there was no significant difference between the two sequences in ADC values of various solid pancreatic lesions (p > 0.05).
Conclusions: Reduced FOV DWI of the pancreas provides better anatomic structure visualization, reduced artifacts and better overall image quality as compared to large FOV DWI. ADC values were not significantly different between the two sequences. Reduced FOV DWI could be included in the standard MRI protocol of the pancreas.
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