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ETD

Digital archive of theses discussed at the University of Pisa

 

Thesis etd-10122007-083130


Thesis type
Tesi di dottorato di ricerca
Author
ASSO, VALENTINA
URN
etd-10122007-083130
Thesis title
New non-peptidic inhibitors of â secretase as potential anti-alzheimer agents
Academic discipline
CHIM/08
Course of study
SCIENZA DEL FARMACO E DELLE SOSTANZE BIOATTIVE
Supervisors
Relatore Prof. Macchia, Marco
Keywords
  • â secretase
  • Alzheimer
  • BACE
Graduation session start date
07/05/2007
Availability
Full
Summary
The studies were carried out in collaboration with Siena Biotech and involve the identification of novel small molecules with potential of modulating diseases. On the basis of well known patented compounds we focused our attention on the synthesis of : 4-aminopiperidine derivatives, tetraline derivatives and carbazole derivatives.
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