ETD

Archivio digitale delle tesi discusse presso l'Università di Pisa

Tesi etd-10012019-112959


Tipo di tesi
Tesi di laurea magistrale LM5
Autore
MUGNAI, ILARIA
URN
etd-10012019-112959
Titolo
Valutazione degli effetti di lidocaina e dexmedetomidina sulla qualità di risveglio ed estubazione nel cane
Dipartimento
SCIENZE VETERINARIE
Corso di studi
MEDICINA VETERINARIA
Relatori
relatore Prof.ssa Briganti, Angela
correlatore Dott. Degani, Massimiliano
Parole chiave
  • qualità del risveglio
  • lidocaina
  • estubazione
  • dexmedetomidina
  • cane
  • anestesia generale
Data inizio appello
25/10/2019
Consultabilità
Non consultabile
Data di rilascio
25/10/2089
Riassunto
Introduction and aim of the study: the IV administration of lidocaine and dexmedetomidine have been proposed as a methods to improve intubation’s quality of the dog. The aim of this study is to compare the efficacy of the EV administration of lidocaine or dexmedetomidine to improve the quality of recovery and extubatione in dog.
Material and methods: were recruited twenty dogs owned, of various breeds, age and weight, referred to the veterinary hospital “Mario Modenato” to undergo surgical or diagnostic procedures, lasting at least 1 hour. All dogs were premedicated with methadone (0.2 mg/kg EV/IM) and dexmedetomidine (0.5 mcg/kg EV or 5 mcg/kg IM) and induced with Propofol EV to effect to allow orotracheal intubation. Subjects were randomly divided into four groups: LIDO1 group (lidocaine 1 mg/kg EV), LIDO2 group (lidocaine 2 mg/kg EV), DEX group (dexmedetomidine 0.5 mcg/kg EV), and CON group (saline solution). At the end of surgery, with an isofluorane breath of 1.0, the bolus was administered in 2 minutes (T0). Cardiovascular and respiratory parameters were recorded, starting with T0, every 5 minutes, to the extubation. The quality of awakening and extubation were evaluated with two scales.
Results: In both study groups there was no significan improvement in the quality of awakening, nor in preventing or alleviating cough. No changes were found in HR, PAI, RR and EtCO2.
Conclusion: Intravenous administration of lidocaine (1 mg/kg e 2 mg/kg) and dexmedetomidine (0,5 mcg/kg) did not significantly improve the recovery and extubation in dogs
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