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Digital archive of theses discussed at the University of Pisa

 

Thesis etd-09152023-100633


Thesis type
Tesi di laurea magistrale
Author
DELL'AMICO, MATTIA
URN
etd-09152023-100633
Thesis title
Design and fabrication of 3D printed deformable model of patient-specific left atrium for PIV investigation
Department
INGEGNERIA DELL'INFORMAZIONE
Course of study
INGEGNERIA BIOMEDICA
Supervisors
relatore Prof. Vozzi, Giovanni
relatore Prof.ssa Celi, Simona
relatore Ing. Gasparotti, Emanuele
relatore Ing. Fanni, Benigno Marco
Keywords
  • PIV
  • 3D printing
  • LAA
Graduation session start date
06/10/2023
Availability
Withheld
Release date
06/10/2093
Summary
The main cause of myocardial infarction is the formation of blood clots inside the Left Atrium Appendage (LAA), which enter the bloodstream due to Atrial Fibrillation (AF) and are the main cause of stroke. Biomedical engineering can help correlate the associated risk by studying the fluid dynamics of the LAA. In this thesis work, the Particle Image Vecimetry (PIV) technique was used to study fluid dynamics in a deformable model of a patient-specific left atrium. Starting from CT images, a segmentation was performed and then the final model was created with a flange to connect it to the fluid dynamic sey-up. Because of its special optical properties, Sylgard 184 was cast to make the model. The casting required an outer mold and an inner mold to form outer and inner surface. Both molds were also made of silicone to make them reusable and to facilitate removal of the model. The finished phantom was then used for acquisition with the PIV technique.
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