• Cyclothymia
• Emotional Dysregulation
• Emotionality

Cyclothymia, among mood disorders, is probably the most neglected in terms of research. Current definitions and diagnostic criteria elude its core of dysregulated mood and often fail to intercept its most common behavioral manifestations.
We recruited 131 individuals with diagnosis of cyclothymia and evaluated the temperamental, emotional, anxious and chronobiological phenotypes. The variance in these parameters was explained by two factors: the level of baseline mood-psychomotor tone and the degree of emotional reactivity. Emotional reactivity tightly related to all internalizing comorbidities of cyclothymia, while a high baseline mood-psychomotor tone was connected to externalizing psychopathological features and to the morningness tendency. Cluster B personality disorders Borderline and Antisocial appeared to differ from cyclothymia not in terms of quality but just in quantity of the loadings of the two factors extracted. These two factors act as good predictors for specific comorbidities and represent a possibile target for biologic research.