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Tesi etd-03232015-114711


Thesis type
Tesi di dottorato di ricerca
Author
CRISTOFARO, MARIO
URN
etd-03232015-114711
Title
Chronic Fatigue Syndrome: A Proteomic Approach
Settore scientifico disciplinare
BIO/10
Corso di studi
NEUROSCIENZE E SCIENZE ENDOCRINOMETABOLICHE
Commissione
tutor Prof. Lucacchini, Antonio
Parole chiave
  • Chronic Fatigue Syndrome
  • CFS
  • Proteomic
  • biochemistry
  • biomarker
Data inizio appello
06/04/2015;
Consultabilità
completa
Riassunto analitico
Our study moves from the previous research conducted by Ciregia which, however, was limited to only a couple of monozygotic twins discordant for CFS. The study of 2013 pointed out some proteins which are useful both to define a panel of potential diagnostic biomarkers and to shed new light on the comprehension of the pathogenetic pathways of CFS [136]. <br>Our research was born, then, from the need to extend the results obtained from the twin study on a larger number of subjects with similar medical history and continue the search for biomarkers useful for both diagnosis and therapy of this syndrome.<br>Using different techniques (2-DE; western blot and ELISA – kit ), with a proteomic approach, we tried to confirm the biomarkers found in past studies and to seek new ones. <br>
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