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Tesi etd-03212012-232636


Thesis type
Tesi di specializzazione
Author
PASQUARIELLO, ROSA
URN
etd-03212012-232636
Title
Role of MRI in term newborn hypoxic-ischemic encephalopathy: correlation with motor outcome
Struttura
MEDICINA E CHIRURGIA
Corso di studi
RADIODIAGNOSTICA
Supervisors
relatore Prof. Bartolozzi, Carlo
Parole chiave
  • basal ganglia
  • motor outcome
  • term newborn
  • hypoxic-ischemic encephalopathy
Data inizio appello
13/04/2012;
Consultabilità
Completa
Riassunto analitico
Abstract
Objectives: To correlate the site and severity of brain lesions seen on magnetic resonance imaging (MRI) with the general movements, Hammersmith scoring and motor outcome in term new-borns with ipoxic-ischemic encephalopathy.
Materials and methods: in the period between April 2009 and February of 2012 we studied whit MR imaging twenty-three term neonates (14M e 9F) with diagnosis of encephalopathy according to the criteria of Sarnat and Sarnat. Brain MR scan has been performed within the first 3 postnatal weeks and scored in 5 patterns of injury based on a modified classification system of Okereafor et al. General movements as at both 1 and 3 postnatal months, Hammersmith scoring as at 1week, 1 and 3 postnatal months have been evaluated. Motor outcome was assessed as at 6 both and 12 months.
Conclusion: in term infants with HIE, the site and severity of brain lesions seen on early MRI are correlated with general movements, Hammersmith scoring and motor outcome.
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