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Tesi etd-03102023-103917


Tipo di tesi
Tesi di laurea magistrale
Autore
APREA, ELENA
URN
etd-03102023-103917
Titolo
Bioresorbable optical filters for dual-chamber pacing implementation in light-triggered cardiac pacemaker
Dipartimento
INGEGNERIA DELL'INFORMAZIONE
Corso di studi
BIONICS ENGINEERING
Relatori
relatore Prof. Micera, Silvestro
relatore Prof. Rogers, John A.
Parole chiave
  • bioelectronics
  • bioresorbable materials
  • cardiac pacemaker
  • dual-chamber
  • optical filters
Data inizio appello
21/04/2023
Consultabilità
Non consultabile
Data di rilascio
21/04/2093
Riassunto
Bioresorbable materials have emerged in recent years as a powerful tool for fabricating implantable biomedical devices for short-term applications without secondary surgical extraction and with a reduced risk of infection. A fitting example where these materials are beneficial is the temporary transcutaneous cardiac pacemaker employed during surgical recovery when arrhythmias can occur.

The literature on the bioresorbable version of this type of device, however, does not implement dual-chamber (atrio-ventricular) pacing, which is the gold standard for commercial pacemakers because it restores the normal electrophysiological function of the cardiac conduction system.

Here, a novel method is presented for implementing dual-chamber pacing in a light-triggered cardiac pacemaker prototype through bioresorbable optical filters. The band-stop optical filters have been engineered, fabricated, tested, and integrated with pacing devices and an adhesive interface, with the final aim of selectively activating the atrium or ventricle of the heart by letting through a specific wavelength of light radiation.

The results show that the filters realized can screen the desired wavelengths and that their integration into the device allows the pacing required. Future system developments will take advantage of the filters created to sequentially activate the heart to resemble the activity of cardiac pacemakers used in clinical practice.
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