Thesis etd-10262023-130849 |
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Thesis type
Tesi di specializzazione (5 anni)
Author
MASSA, VALENTINA
URN
etd-10262023-130849
Thesis title
Concordance of PD-L1 combined positive score analysis between primary gastric cancer and matched peritoneal metastasis.
Department
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Course of study
ONCOLOGIA MEDICA
Supervisors
relatore Prof. Masi, Gianluca
relatore Dott. Fornaro, Lorenzo
relatore Dott. Fornaro, Lorenzo
Keywords
- Gastric cancer
- PD-L1 combined positive score
- peritoneal metastasis
Graduation session start date
14/11/2023
Availability
Withheld
Release date
14/11/2093
Summary
PD-L1 is an established predictive immunohistochemical biomarker of response to immune checkpoint inhibitors. At present, PD-L1 is routinely assessed on biopsy samples of advanced gastroesophageal cancer patients before initiating first-line treatment. However, PD-L1 is still a suboptimal biomarker, due to changing cut-off values and scoring systems, interobserver and interlaboratory variability.
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