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Tesi etd-09202014-132242


Thesis type
Tesi di laurea specialistica LC6
Author
ROSSI, LEONARDO
URN
etd-09202014-132242
Title
Surgical management of ganglioneuroma: our experience and literature review.
Struttura
RICERCA TRASLAZIONALE E DELLE NUOVE TECNOLOGIE IN MEDICINA E CHIRURGIA
Corso di studi
MEDICINA E CHIRURGIA
Commissione
relatore Spinelli, Claudio
Parole chiave
  • incidentaloma
  • ganglioneuroma
  • surgical resection
Data inizio appello
14/10/2014;
Consultabilità
completa
Riassunto analitico
Background and aims: ganglioneuromas are benign tumors which origin from the <br>neural crest. This tumor affects mainly young patients rather than adult ones, and its <br>most frequent localizations are mediastinum, retroperitoneum, adrenal glands and <br>cervical region. Usually, ganglioneuromas are discovered as incidentalomas since <br>they are often asymptomatic, even if they could present sympathetic or mass-related <br>symptoms. To obtain a definitive diagnosis, histological exam is necessary. The <br>surgical excision is the chosen treatment and it offers an excellent prognosis. <br>Methods: we conducted a retrospective analysis of our cases of ganglioneuroma <br>from 2004 to 2014; this study aims to compare our experience’s data with literature <br>review (2000-2014). Data about patients’ features, tumors’ localization, symptoms, <br>treatment and follow-up were analyzed and reported in detailed tables. <br>Results: between 2004-2014 we treated 12 patients affected by ganglioneuroma. For <br>all of them the diagnosis was incidental; 7 out of 12 (58.3%) patients presented an <br>adrenal mass; in 2 patients (16.7%) the tumor was localized in cervical region; in <br>other 2 patients (16.7%) the tumor was in the retroperitoneum and one patient (8.3%) <br>presents a ganglioneuroma in the costo-vertebral space. All our patients underwent <br>surgical removal and none of them present surgery-related complications or <br>recurrences to date. <br> <br>Conclusions: our data widen the knowledge about ganglioneuroma and confirm that <br>the surgical approach has an excellent prognosis with very low incidence of surgery-<br>related complications and recurrences
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