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Digital archive of theses discussed at the University of Pisa

 

Thesis etd-06222017-122057


Thesis type
Tesi di specializzazione (5 anni)
Author
MURATORI, ENRICO
URN
etd-06222017-122057
Thesis title
Partial pharyngolaryngectomy in advanced hypopharyngeal cancer: 57 consecutive reconstructions with infrahyoid flap
Department
PATOLOGIA CHIRURGICA, MEDICA, MOLECOLARE E DELL'AREA CRITICA
Course of study
OTORINOLARINGOIATRIA
Supervisors
relatore Prof. Gallo, Oreste
relatore Dott. Dolivet, Gilles
Keywords
  • hypopharyngeal carcinoma
  • infrahyoid flap
  • laryngectomy
  • partial
  • pedicled flap
  • pharyngectomy
Graduation session start date
11/07/2017
Availability
Full
Summary
Aims. We evaluated a cohort of advanced hypopharyngeal squamous cell carcinoma, treated with conservative surgery, reconstruction with infrahyoid flap and radio-chemotherapy.
Methods. We used partial laryngopharyngectomy and radio-chemotherapy to treat fifty-seven patients with stage III-IV hypopharyngeal SCC from November 1994 to December 2011. Clinical examination and speech therapy evaluation were used for estimation of laryngeal function.
Results. All patients received a partial laryngopharyngectomy. All patients underwent neck dissection; 56 patients received bilateral neck dissection. Reconstruction was achieved by infra-hyoid flap. Five-year overall and disease-specific survival rates were 54,4% and 61,4%, respectively. Successful laryngeal function preservation with complete five-years remission was achieved in 44% of the patients.
Conclusion. Selected even if advanced carcinomas of the hypopharynx maybe treated with partial laryngopharyngectomy with reconstruction with pedicled flap. Both oncological and functional results showed a good outcome.
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