Thesis etd-06212017-122832 |
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Thesis type
Tesi di specializzazione (5 anni)
Author
MANCINI, NICCOLO'
URN
etd-06212017-122832
Thesis title
Scaffold bioriassorbibili: le aspettative sono state mantenute?
Department
PATOLOGIA CHIRURGICA, MEDICA, MOLECOLARE E DELL'AREA CRITICA
Course of study
MALATTIE DELL'APPARATO CARDIOVASCOLARE
Supervisors
relatore Prof. Marzilli, Mario
correlatore Prof.ssa Petronio, Anna Sonia
correlatore Prof.ssa Petronio, Anna Sonia
Keywords
- cardiopatia ischemica
- optical coherence tomography
- scaffold bioriassorbibili
Graduation session start date
10/07/2017
Availability
Withheld
Release date
10/07/2087
Summary
Background: Bioresorption of bioresorbable vascular scaffold (BVS) may lead to late coronary lumen enlargement through positive vessel remodelling. We aimed to investigate with serial intracoronary imaging the interaction between BVS and coronary artery wall in patients with complex coronary lesions.
Methods: We performed optical coherence tomography (OCT) two years after BVS implantation in patients with baseline and postprocedural OCT or intravascular ultrasound imaging. The change in scaffold diameter at the proximal and distal radiopaque markers was measured. We also assessed abluminal scaffold area, coronary flow area, and neointimal area with OCT, and minimum lumen diameter (MLD) and late lumen loss (LLL) with quantitative coronary angiography.
Methods: We performed optical coherence tomography (OCT) two years after BVS implantation in patients with baseline and postprocedural OCT or intravascular ultrasound imaging. The change in scaffold diameter at the proximal and distal radiopaque markers was measured. We also assessed abluminal scaffold area, coronary flow area, and neointimal area with OCT, and minimum lumen diameter (MLD) and late lumen loss (LLL) with quantitative coronary angiography.
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