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Tesi etd-05192015-123321


Thesis type
Tesi di specializzazione (5 anni)
Author
LANCIONI, MATTEO
URN
etd-05192015-123321
Title
Long term left atrium remodelling after successful reduction of the left ventricular outflow tract obstruction with surgical myectomy in patients with hypertrophic cardiomyopathy.
Struttura
PATOLOGIA CHIRURGICA, MEDICA, MOLECOLARE E DELL'AREA CRITICA
Corso di studi
MALATTIE DELL'APPARATO CARDIOVASCOLARE
Commissione
relatore Marzilli, Mario
Parole chiave
  • left atrium remodelling
  • myectomy
  • Hypertrophic cardiomyopathy
Data inizio appello
10/06/2015;
Consultabilità
completa
Riassunto analitico
The left atrium (LA) enlargement in patients with hypertrophic cardiomyopathy (HCM) is a marker of disease progression and adverse prognosis. LA dilatation in patients with HCM is multifactorial and related to left ventricular outflow tract obstruction (LVOT), Mitral regurgitation (MR), left ventricular diastolic dysfunction, LV raised endiastolic pressures and genetic individual factors. Surgical myectomy is the gold standard procedure for the reduction of the LVOT obstruction, reducing also SAM-related mitral regurgitation (MR). Long term effects on the LA size and remodeling following successful surgical myectomy are unknown.
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