• biomimetic
• feedback
• intraneural
• prostheses
• prosthesis
• sensory

The aim of this thesis is to improve the sensibility and dexterity of trans-radial amputees using prostheses with sensory feedback, while eliciting sensations as natural as possible.
A model simulating a population of afferent fibers from the hand has been used as source for the encoded information, the model is able to evaluate responses to touch stimuli according to their spatial and temporal features; multiple modulation strategies have been devised, according to the source of information and the affected stimulation parameter.
The new modulation techniques developed have been evaluated on a subject with a trans-radial amputation and an intraneural implant, the results highlight improved performances in functional tests, enhanced sensibility and, as a result, a reduction of abnormal phantom limb perceptions, suggesting a better embodiment.