Thesis etd-03012024-114240 |
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Thesis type
Tesi di laurea magistrale
URN
etd-03012024-114240
Thesis title
Interacting with peritumoral parvalbumin interneurons to counteract Glioblastoma growth
Department
BIOLOGIA
Course of study
NEUROSCIENCE
Supervisors
.
relatore Vannini, Eleonora
Keywords
- GABA
- Glioblastoma
- inhibitory system
- mouse model
Graduation session start date
08/04/2024
Availability
Withheld
Release date
08/04/2064
Abstract (Inglese)
Abstract (Italiano)
This project aimed at dissecting the role of parvalbumin interneurons during GB growth. To address this issue, I used techniques such as chemogenetics, motor tests, MRI and immunohistochemistry analyses.
Given the complex relationship between GB and the peritumoral tissue, it is of paramount importance to understand and dissect the role of all the players in order to add useful information to develop more effective therapeutic approaches aimed at ameliorating patients’ quality of life and survival.
Given the complex relationship between GB and the peritumoral tissue, it is of paramount importance to understand and dissect the role of all the players in order to add useful information to develop more effective therapeutic approaches aimed at ameliorating patients’ quality of life and survival.
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