ETD system

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Tesi etd-01252019-144220


Thesis type
Tesi di laurea magistrale
Author
PELLEREJ DI BROCCHETTI, FRANCESCO LUIGI
URN
etd-01252019-144220
Title
FABRICATION AND CHARACTERIZATION OF A MICROFLUIDIC NETWORK MADE OF ELASTIN-LIKE POLYPEPTIDES (ELP) AND GRAPHENE OXIDE(GO)
Struttura
INGEGNERIA DELL'INFORMAZIONE
Corso di studi
INGEGNERIA BIOMEDICA
Supervisors
relatore Prof. Vozzi, Giovanni
Parole chiave
  • Graphene Oxide
  • Elastin-Like Polypeptides
  • Biofabrication
  • Organ on a chip
Data inizio appello
15/02/2019;
Consultabilità
Secretata d'ufficio
Data di rilascio
15/02/2089
Riassunto analitico
Microfluidics refers to a set of technologies for the manipulation of small fluid volumes (mL) within artificially microsystems. Among the microfluidic systems, there are Organ-On-Chip (OOC), microfluidic devices for culturing living cells in continuously perfusion, with the aim of modelling the physiological functions of tissues and organs. OOC devices can be used not only to elucidate the mechanisms involved in the development of a blood vessel but also as experimental platforms for vascular disease models and drug screening.
This thesis is focused on the fabrication of a microfluidic system using a group of materials called Elastin-Like Polypeptides (ELP). In particular, a material capable of self-assembling (ELK1) inside graphene oxide (GO) has been used. In order to achieve this objective, diffusivity at the membrane interface and biofabrication tests were carried out.
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