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Tesi etd-01202012-095632


Thesis type
Tesi di dottorato di ricerca
Author
JUMDE, RAVINDRA
email address
ravi_jumde@yahoo.co.in
URN
etd-01202012-095632
Title
SUPPORTED LIGANDS AND ORGANOCATALYSTS FOR ENANTIOSELECTIVE TRANSFORMATIONS: A PRACTICAL FEASIBILITY PERSPECTIVE
Settore scientifico disciplinare
CHIM/06
Corso di studi
SCIENZE CHIMICHE
Commissione
tutor Prof. Pini, Dario
correlatore Dott. Mandoli, Alessandro
controrelatore Prof. Benaglia, Maurizio
Parole chiave
  • supported catalysts
  • click chemistry
  • Cinchona alkaloids
  • Asymmetric organocatalysis
Data inizio appello
30/01/2012;
Consultabilità
completa
Riassunto analitico
A new approach for the immobilization onto organic insoluble polymers of Cinchona alkaloid derivatives was developed and the resulting insoluble polymer-bound (IPB) systems were used as enantioselective organocatalysts in different metal-free asymmetric transformations. Landmarks of this work were the scalable preparation of the IPB derivatives, the attainment of excellent catalytic performance (up to 97% ee) in selected enantioselective processes (dimerization of ketenes and a-amination of 2-oxindoles) and extended serviceability (up to 100 reaction cycles and 5300 h reaction time) of the supported catalysts.
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