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Tesi etd-01122016-103438


Thesis type
Tesi di laurea specialistica LC6
Author
MARRACCINI, LUCA
URN
etd-01122016-103438
Title
Pretrattamento ormonale in pazienti con ridotta riserva ovarica che si sottopongono a cicli di procreazione medicalmente assistita: uno studio retrospettivo
Struttura
DIPARTIMENTO DI MEDICINA CLINICA E SPERIMENTALE
Corso di studi
MEDICINA E CHIRURGIA
Commissione
relatore Prof. Gadducci, Angiolo
correlatore Dott. Cela, Vito
Parole chiave
  • IVF outcome
  • Poor ovarian responders
  • POF premature ovarian failure
  • PMA procreazione medicalmente assistita
  • pretrattamento ormonale
  • FSH
  • AMH
  • estrogeni
  • progesterone
  • ovociti
  • embrioni
  • gravidanza
Data inizio appello
02/02/2016;
Consultabilità
parziale
Data di rilascio
02/02/2019
Riassunto analitico
Premature ovarian failure(POF)is a disorder characterised by the cessation of ovarian function before the age of 40,with amenorrhoea,hypergonadotropinism and hypoestrogenism.It affects1-3%women of reproductive age.Several aetiologies have been postulated but most of the cases are idiopathic.Actually no treatment has been conclusively resulted in enhancement of fertility,thus the use of donor eggs is often the only possibility.Several studies showed, also,that FSH level for a good ovarian response could be10mUI/mL.Hormone replacement therapy in POF could correct the endocrine defect and may be a possibility to improve fertility.The aim of this study is to evaluate if a pre-treatment hormone therapy in patients with hypergonadotropic hypogonadism just prior to their ovarian hyperstimolation cycle can decrease FSH basal level, improve number and quality of retrieved oocytes and finally increase pregnancy rate.This is a retrospective study conduct in our Assisted Reproductive Centre of University of Pisa.
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