logo SBA

ETD

Archivio digitale delle tesi discusse presso l’Università di Pisa

Tesi etd-11292018-163622


Tipo di tesi
Tesi di laurea magistrale
Autore
GASPARONI, ALBERTA
Indirizzo email
alberta.gasparoni@gmail.com
URN
etd-11292018-163622
Titolo
BIODISPONIBILITA DEI NUTRACEUTICI: ANALISI DEI PRODOTTI UTILIZZATI PER PREVENIRE L'INSORGENZA DI PATOLOGIE CARDIOVASCOLARI
Dipartimento
FARMACIA
Corso di studi
SCIENZE DELLA NUTRIZIONE UMANA
Relatori
relatore Prof.ssa La Motta, Concettina
correlatore Dott.ssa Nicastro, Mariaconcetta
Parole chiave
  • PRODOTTI NUTRACEUTICI
  • BIODISPONIBILITà
  • MALATTIE CARDIOVASCOLARI
  • COLESTEROLO
  • IPERTENSIONE
  • HERBAL BIOENHANCER
  • NANOFORMULAZIONI
Data inizio appello
17/12/2018
Consultabilità
Non consultabile
Data di rilascio
17/12/2088
Riassunto
The bioavailability of nutraceuticals is a very important topic to consider because most of the phytotherapeutic compounds have poor pharmacokinetics and absorption. The inefficiency of some nutraceuticals may be linked to the action of gastric juices, cytochromes, intestinal microbiota but also from other systems present in the intestine like the ATP-binding cassettes that remove the compounds inserted into the enterocytes. To improve the bioavailability of a nutraceutical can be used substances that increase it, named bioenhancer herbs. For this purpose it is also possible to use liposomes, or better yet, phytosomes, or particular galenic techniques based on the function of the preparation. In recent years the impact of cardiovascular disease has increasingly become one of the leading causes of death. In this case the use of nutraceuticals is constantly increasing because they can improve the quality of life without side effects, typical of drugs, and are also better assimilated and used by the body. The main nutraceuticals are used to improve the lipid profile through inhibition: hepatic synthesis of cholesterol and intestinal absorption of cholesterol; or they can reduce hypertension and they may contain more active ingredients in the same supplement.
File