Tesi etd-06212017-122832 |
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Tipo di tesi
Tesi di specializzazione (5 anni)
Autore
MANCINI, NICCOLO'
URN
etd-06212017-122832
Titolo
Scaffold bioriassorbibili: le aspettative sono state mantenute?
Dipartimento
PATOLOGIA CHIRURGICA, MEDICA, MOLECOLARE E DELL'AREA CRITICA
Corso di studi
MALATTIE DELL'APPARATO CARDIOVASCOLARE
Relatori
relatore Prof. Marzilli, Mario
correlatore Prof.ssa Petronio, Anna Sonia
correlatore Prof.ssa Petronio, Anna Sonia
Parole chiave
- optical coherence tomography
- cardiopatia ischemica
- scaffold bioriassorbibili
Data inizio appello
10/07/2017
Consultabilità
Non consultabile
Data di rilascio
10/07/2087
Riassunto
Background: Bioresorption of bioresorbable vascular scaffold (BVS) may lead to late coronary lumen enlargement through positive vessel remodelling. We aimed to investigate with serial intracoronary imaging the interaction between BVS and coronary artery wall in patients with complex coronary lesions.
Methods: We performed optical coherence tomography (OCT) two years after BVS implantation in patients with baseline and postprocedural OCT or intravascular ultrasound imaging. The change in scaffold diameter at the proximal and distal radiopaque markers was measured. We also assessed abluminal scaffold area, coronary flow area, and neointimal area with OCT, and minimum lumen diameter (MLD) and late lumen loss (LLL) with quantitative coronary angiography.
Methods: We performed optical coherence tomography (OCT) two years after BVS implantation in patients with baseline and postprocedural OCT or intravascular ultrasound imaging. The change in scaffold diameter at the proximal and distal radiopaque markers was measured. We also assessed abluminal scaffold area, coronary flow area, and neointimal area with OCT, and minimum lumen diameter (MLD) and late lumen loss (LLL) with quantitative coronary angiography.
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