Tesi etd-05122013-155725 |
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Tipo di tesi
Tesi di laurea magistrale
Autore
NAPPI, JADRANKA
URN
etd-05122013-155725
Titolo
Analysis of genomic and metagenomic libraries of marine epiphytic bacteria to isolate and characterize the antinematode activity when screened against Caenorhabditis elegans.
Dipartimento
BIOLOGIA
Corso di studi
BIOLOGIA MARINA
Relatori
relatore Prof. Verni, Franco
Parole chiave
- marine bacteria
- functional metagenomic screen
- functional genomic screen
- fosmid libraries
- Caenorhabditis elegans
- antinematode
- marine bioactives
Data inizio appello
13/06/2013
Consultabilità
Non consultabile
Data di rilascio
13/06/2053
Riassunto
The main purpose of this thesis was to screen genomic and metagenomic libraries of epiphytic bacterial communities previously isolated from the surface of marine seaweed Ulva australis and Delisea pulchra. Through functional screening against the nematode Caenorhabditis elegans, the bacterial clones at the subject of this thesis have been characterized for their antinematodal activity. Here I showed that marine microorganisms are a source of bioactivity against the nematode C. elegans and those bacterial secondary metabolites might lead in the long terms to pharmaceuticals and better nematode management strategies.
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