ETD

Archivio digitale delle tesi discusse presso l'Università di Pisa

Tesi etd-02162016-182316


Tipo di tesi
Tesi di dottorato di ricerca
Autore
GABRIELE, MORENA
URN
etd-02162016-182316
Titolo
Effetti nutraceutici di sostanze naturali su cellule endoteliali esposte ad infiammazione, stress ossidativo o stress del reticolo endoplasmatico
Settore scientifico disciplinare
BIO/12
Corso di studi
FISIOPATOLOGIA CLINICA
Relatori
tutor Prof. Palombo, Carlo
tutor Dott.ssa Pucci, Laura
Parole chiave
  • nutraceuticals
  • inflammation
  • HMEC-1
  • functional foods
  • ER stress
  • EPCs
  • endothelial activation and dysfunction
  • CAA-RBC
  • oxidative stress
Data inizio appello
02/03/2016
Consultabilità
Completa
Riassunto
Increasing evidence has demonstrated that dietary products and their active components are independently or jointly responsible for the apparent reduction in cardiovascular diseases (CVDs) risk. Endothelial dysfunction plays an important role in the development and progression of several chronic diseases including CVDs. Since endothelial dysfunction is currently considered a reversible phenomenon, there is a growing interest in the endothelial effects of nutraceuticals in order to provide powerful insights on their protective role. This review summarizes the healthful effects of several nutraceuticals, paying particular attention to our results focused on the protective effects of Citrus bergamia fruit, bee-pollen, and fermented foods on endothelial cells.
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