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In the present work, we describe a possible formal semantics for Molecular Interaction Maps (MIMs), which are standard diagrams, used by biologists to depict interactions at molecular level within a cell environment. First we describe MIM notation in details, then we describe the Calculi of Looping Sequences (CLS), a family of formal languages which models biological systems, whose semantics is a transition systems. Finally, we give a possible formal semantics in CLS for MIMs.